Abstract
In this paper, ZnO nanoparticles (NPs) have been synthesized using extract of leaves of Azadirachta indica (Neem tree), Ficus benghalensis (banyan tree) and Tabernaemontana divericata (Chameli). These green synthesized NPs have been studied for anticancer and supercapacitor applications. The synthesized NPs have been characterized using various techniques such as UV–Visible spectroscopy, FTIR, powder x-ray diffraction (PXRD), scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), field emission scanning electron microscopy (FE-SEM). The green synthesized nanoparticles with Azadirachta indica have been used to investigate the cell viability of human lung adenocarcinoma (A549 cells) using MTT assay. Herein, a comparative anticancer study has been performed using only leaves extract of Azadirachta indica, ZnO NPs synthesized with leaves extract of Azadirachta indica and chemical-wet method respectively. The viability of lung cancer cell lines (A549) decreases significantly with ZnO NPs synthesized with leaves extract as compare to only extract (OE) of leaves of Azadirachta indica (Neem tree). The cell viability does not changes with concentration of ZnO NPs synthesized with chemical wet method. So, the ZnO NPs synthesized with chemical-wet method has been used as a control for this anticancer activity. The cell viability also decreases with an incubation period of 48 h at the concentration (100, 150, 200 and 250 µg/mL) of ZnO NPs. The IC50 value for zinc oxide nanoparticles prepared with 1 mL of leaves extract (L1-NPs) has been obtained 138.50µg/mL at 48 h incubation. Herein, the flow cytometry study has also been performed. The ZnO NPs synthesized with leaves extract of Ficus benghalensis (banyan tree) and Tabernaemontana divericata (Chameli) have been studied for supercapacitor applications. The specific capacitance (Cs) has been determined using cyclic voltammetry (CV) technique. Herein, the calculated values of specific capacitance for ZnO NPs synthesized with Ficus benghalensis (banyan tree) are 6.318 F g-1 at 20 mV/s, 4.363 F g-1 at 40 mV/s, 3.611 F g-1 at 60 mV/s, 3.222 F g-1 at 80 mV/s and 2.972 F g-1 at 100 mV/s respectively. Similarly, the specific capacitance have been calculated using glassy carbon electrode (GCE), which has been drop casted by ZnO NPs synthesized with Tabernaemontana divericata. Herein, the calculated values of specific capacitance are 535.7142 F g-1, 401.7857 F g-1, 304.7619 F g-1, 229.9107 F g-1 and 189.2857 F g-1 respectively. Herein, the highest energy density and power density have also been determined 36.4583Wh/kg and 65.6249W/kg respectively at 20 mV/s. Whereas, the values of highest energy density varies in the range from 1.0620 Wh/kg to 0.4996 Wh/kg for ZnO NPs synthesized with Ficus benghalensis. It means, the ZnO NPs synthesized with Tabernaemontana divericata can be used as an electrode material for high performance supercapacitors and ZnO NPs synthesized with leaves extract of Azadirachta indica can be used as nanomedicine for lung cancer.

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