Dr. Giovanni Pagano has been active for 40 years in studies of the adverse effects of  several xenobiotics and complex mixtures. After retiring from the Italian National Cancer Institute in Naples, He has remained active in international research activities. To date He is committed as a Research Contractor at the Department of Chemical Sciences, Federico II University of Naples, Naples, Italy. The subject of this presentation – REEs – has been investigated within an international research team, since an early paper in 2010.